Week 1 will feature four prime-time games between Thursday and Monday.
The playoff rematch between Buffalo and Baltimore on Sunday night looms as the game of the weekend.
One of our experts picked nearly 73% of the games correctly in 2024.
Since the Philadelphia Eagles won Super Bowl 59 in February, a full 207 days have passed ahead of their 2025 regular-season kickoff opener against the Dallas Cowboys on Thursday night. In between? There was a draft, free agency, Micah Parsons got traded from the Cowboys, Taylor Swift and Travis Kelce got engaged, Nike rolled out some slick new uniforms … but no legit NFL football.
But now our cups runneth over. Following Eagles-Cowboys, the Week 1 smorgasbord rolls onward Friday night, when Kelce’s Kansas City Chiefs face the Los Angeles Chargers in São Paulo, and Swift will reportedly be in attendance at Corinthians Arena.
Sunday’s 13-game stack kicks off with Pittsburgh Steelers QB Aaron Rodgers’ return to ‘JetLife’ Stadium and ends with a playoff rematch between former MVP Lamar Jackson’s Baltimore Ravens and reigning MVP Josh Allen’s Buffalo Bills.
Week 1 ends Monday night in Chicago, where the new-look Bears will host the Minnesota Vikings in QB J.J. McCarthy’s first regular-season start.
Can’t. Wait.
(But to tide you over in the interim, Week 1 picks from USA TODAY Sports’ panel of NFL experts.)
(Odds provided by BetMGM)
Dallas Cowboys at Philadelphia Eagles
Kansas City Chiefs at Los Angeles Chargers
New York Giants at Washington Commanders
Tampa Bay Buccaneers at Atlanta Falcons
Las Vegas Raiders at New England Patriots
Arizona Cardinals at New Orleans Saints
Pittsburgh Steelers at New York Jets
Miami Dolphins at Indianapolis Colts
Cincinnati Bengals at Cleveland Browns
Carolina Panthers at Jacksonville Jaguars
San Francisco 49ers at Seattle Seahawks
Tennessee Titans at Denver Broncos
Detroit Lions at Green Bay Packers
Houston Texans at Los Angeles Rams
Baltimore Ravens at Buffalo Bills
Minnesota Vikings at Chicago Bears
